胃腸腫瘤中心二病區(qū)科主任、外科教研室主任、主任醫(yī)師、教授、博士生導(dǎo)師、腫瘤學(xué)博士?，F(xiàn)任CJCR雜志編輯部主任、中國醫(yī)療保健國際交流促進(jìn)會(huì)結(jié)直腸病分會(huì)主任委員、中國抗癌協(xié)會(huì)期刊出版專委會(huì)主任委員、中國抗癌協(xié)會(huì)胃癌專業(yè)委員會(huì)委員。主要從事胃腸腫瘤的外科及相關(guān)研究工作，追蹤國際腫瘤治療前沿，參與消化道腫瘤治療的眾多新領(lǐng)域。特長于胃腸道腫瘤的根治手術(shù)、腹腔鏡微創(chuàng)手術(shù)、早期胃癌功能保留手術(shù)、低位直腸保肛等術(shù)式。追求手術(shù)的微創(chuàng)與精細(xì)，注重患者神經(jīng)功能保護(hù)及生活質(zhì)量。對(duì)胃腸道手術(shù)有透悟的理解和嫻熟的技術(shù)。主攻胃腸腫瘤的基礎(chǔ)及臨床轉(zhuǎn)化研究。如胃癌免疫微環(huán)境圖譜、胃癌淋巴結(jié)轉(zhuǎn)移免疫微環(huán)境特點(diǎn)刻畫、早期胃癌淋巴結(jié)轉(zhuǎn)移特點(diǎn)及預(yù)測模型構(gòu)建、胃癌的免疫治療研究等。近5年作為通訊/并列通訊作者指導(dǎo)發(fā)表多篇有重要影響的學(xué)術(shù)論文。參與/承擔(dān)多個(gè)國家級(jí)研究項(xiàng)目，如國家自然科學(xué)基金重大研究計(jì)劃、國家自然科學(xué)基金面上項(xiàng)目、揚(yáng)帆計(jì)劃臨床技術(shù)創(chuàng)新項(xiàng)目等。作為共同主編或副主編，出版了《普通外科疾病診治思路》、《腫瘤組織標(biāo)本庫常用技術(shù)手冊(cè)》、《Bethesda臨床腫瘤學(xué)手冊(cè)》、《胃癌規(guī)范化手術(shù)》、《結(jié)直腸癌規(guī)范化手術(shù)》等專著或譯著。

近5年代表性論文：

1. Sun C#, Wang A#, Zhou Y#, Chen P, Wang X, Huang J, Gao J, Wang X, Shu L, Lu J, Dai W, Bu Z, Ji J, He J. Spatially resolved multi-omics highlights cell-specific metabolic remodeling and interactions in gastric cancer. Nat Commun. 2023 May 10;14(1):2692.

2. Li J, Sun X, Yang H, Chen J, Bu Z*, Ji J*, Lan X*. Integrated analysis toolkit for dissecting whole-genome-wide features of cell-free DNA. Clin Transl Med. 2023 Mar;13(3):e1212.

3. Kang B#, Camps J#, Fan B#, Jiang H#, Ibrahim MM, Hu X, Qin S, Kirchhoff D, Chiang DY, Wang S, Ye Y, Shen Z*, Bu Z*, Zhang Z*, Roider HG*. Parallel single-cell and bulk transcriptome analyses reveal key features of the gastric tumor microenvironment. Genome Biol. 2022 Dec 22;23(1):265.

4. Zheng L#, Qin S#, Si W#, Wang A, Xing B, Gao R, Ren X, Wang L, Wu X, Zhang J, Wu N, Zhang N, Zheng H, Ouyang H, Chen K, Bu Z*, Hu X*, Ji J*, Zhang Z*. Pan-cancer single-cell landscape of tumor-infiltrating T cells. Science, 2021 Dec 17;374(6574):abe6474.

5. Cheng S#, Li Z#, Gao R, Xing B, Gao Y, Yang Y, Qin S, Zhang L, Ouyang H, Du P, Jiang L, Zhang B, Yang Y, Wang X, Ren X, Bei JX, Hu X, Bu Z*, Ji J*, Zhang Z*. A pan-cancer single-cell transcriptional atlas of tumor infiltrating myeloid cells. Cell, 2021 Feb 4;184(3):792-8091.

6. Anqiang Wang#, Zhongwu Li#, Meng Wang#, Shuqin Jia#, Jiahu Chen , Ke Ji , Xin Ji , Xianglong Zong, Xiaojiang Wu, Ji Zhang, Ziyu Li, Lianhai Zhang, Ying Hu, Zhaode Bu*, Qi Zheng*, Jiafu Ji*. Molecular Characteristics of Synchronous Multiple Gastric Cancer. Theranostics, 2020 Apr 7;10(12):5489-5500.

7. He Q#, Chen J#, Zhou K#, Jin C#, Wang A, Ji K, Ji X, Zhang J, Wu X, Li X, Bu Z*, Ji J*. Effect of Additional Trastuzumab in Neoadjuvant and Adjuvant Treatment for Patients with Resectable HER2-Positive Gastric Cancer. Ann Surg Oncol, 2021 Aug;28(8):4413-4422.

8. Wei J#, Zhang Y#, Liu Y#, Wang A, Fan B, Fu T, Jia Z, He L, Ji K, Ji X, Wu X, Zhang J, Li Z, Zhang L, Bu Z*, Ji J*. Construction and Validation of a Risk-Scoring Model that Preoperatively Predicts Lymph Node Metastasis in Early Gastric Cancer Patients. Ann Surg Oncol, 2021 Oct;28(11):6665-6672.

9. Liu Z#, Wang A#, Pu Y#, Li Z#, Xue R, Zhang C, Xiang X, E JY, Bu Z*, Bai F*, Ji J*. Genomic and transcriptomic profiling of hepatoid adenocarcinoma of the stomach. Oncogene, 2021 Sep;40(38):5705-5717.