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重癥醫(yī)學(xué)科 - 王宏志

王宏志簡(jiǎn)介

主任醫(yī)師,醫(yī)學(xué)碩士學(xué)位,重癥醫(yī)學(xué)科及靜脈通路中心主任。

1990年畢業(yè)于北京醫(yī)科大學(xué)(現(xiàn)北京大學(xué)醫(yī)學(xué)部),獲醫(yī)學(xué)碩士學(xué)位,畢業(yè)后即就職于北京腫瘤醫(yī)院,從事腫瘤外科臨床一線工作。1996年開始籌建腫瘤醫(yī)院唯一的重癥監(jiān)護(hù)病區(qū)并轉(zhuǎn)入重癥醫(yī)學(xué)領(lǐng)域工作,負(fù)責(zé)各種急危重癥患者的搶救治療以及高危人群的圍術(shù)期監(jiān)護(hù)治療工作。2007-2009年赴美國(guó)匹茲堡大學(xué)醫(yī)學(xué)院重癥醫(yī)學(xué)系訪問(wèn)學(xué)習(xí),對(duì)各系統(tǒng)的器官功能不全及衰竭有了更高的認(rèn)識(shí)和診治水平,尤其在呼吸治療、感染治療、急性腎損傷、創(chuàng)傷與免疫的關(guān)系等方面有較深的造詣。同時(shí)負(fù)責(zé)醫(yī)院心肺復(fù)蘇的培訓(xùn)及教學(xué)工作。對(duì)多部位的動(dòng)脈、深靜脈置管尤其是鎖骨下靜脈的穿刺置管具有很高的操作技巧,對(duì)靜脈輸液港的植入有獨(dú)到的見解和技術(shù)。以第一作者和通訊作者在核心期刊及國(guó)外期刊發(fā)表論文30余篇,內(nèi)容涉及創(chuàng)傷與免疫、輸血與免疫、多原發(fā)大腸癌、感染與腎損傷、藥物與腎損傷、急性腎損傷的防治、靜脈血栓栓塞癥的防治、鎖骨下靜脈置管等多個(gè)領(lǐng)域,其中20篇被SCI收錄。參編、參譯專著多部。

主要社會(huì)兼職:北京大學(xué)重癥醫(yī)學(xué)學(xué)系副主任,中國(guó)抗癌協(xié)會(huì)腫瘤重癥專委會(huì)副主委,北京抗癌協(xié)會(huì)腫瘤重癥專委會(huì)主任委員,中國(guó)中西醫(yī)結(jié)合學(xué)會(huì)周圍血管疾病專業(yè)委員會(huì)靜脈輸液通路專家委員會(huì)常委等十余項(xiàng)社會(huì)兼職。

主要榮譽(yù):北京市抗擊新冠肺炎疫情先進(jìn)個(gè)人,中國(guó)民主同盟抗擊新冠肺炎疫情先進(jìn)個(gè)人,2020年“敬佑生命 榮耀醫(yī)者”“??凭ⅹ?jiǎng)-重癥醫(yī)學(xué)科”,2020年北京大學(xué)優(yōu)秀??漆t(yī)師指導(dǎo)教師,2022年北京大學(xué)優(yōu)秀工會(huì)積極分子等。

發(fā)表論文

1. 第一作者論文

(1)Wang Hongzhi, Huang Xinfu, Lin Benyao, Yang Langui, Yao Lihua. In vitro antitumor activity of tumor-infiltrating lymphocytes from human gastric carcinoma. Chinese J Cancer Res. 1991, 3(2 ):18-21

(2)王宏志 黃信孚 王怡 薛鐘麒 林本耀. 多原發(fā)性大腸癌.中華外科雜志,1995,33(12):765-7

(3)王宏志 胡永華 金山 任宏 楊拔賢. 手術(shù)創(chuàng)傷與圍術(shù)期輸血對(duì)胸部腫瘤患者外周血T淋巴細(xì)胞亞群及自然殺傷細(xì)胞的影響. 中華臨床醫(yī)學(xué)雜志, 2002,1(5):1-4

(4)王宏志 胡永華 宛鳳玲 任宏 張弘 楊拔賢. 手術(shù)創(chuàng)傷對(duì)胸部腫瘤患者血清白細(xì)胞介素2受體、白細(xì)胞介素6和腫瘤壞死因子α表達(dá)的影響. 中國(guó)腫瘤臨床與康復(fù),,2002,9(4):10-2

(5)王宏志* 黃信孚 王怡 季加孚 顧晉. 多原發(fā)大腸癌37例臨床分析。中華普通外科雜志,2003,18(10):588-90

(6)Hong-Zhi Wang*, Xin-Fu Huang, Yi Wang, Jia-Fu Ji, Jin Gu. Clinical features, diagnosis, treatment and prognosis of multiple primary colorectal carcinoma. World Journal of Gastroenterology, 2004,10(14):2136-9

(7)王宏志 任宏. 多種體位鎖骨下靜脈穿刺中心靜脈置管術(shù)的應(yīng)用. 中國(guó)急救醫(yī)學(xué), 2004,24(2):146-7

(8) 王宏志. 體表定位經(jīng)鎖骨下靜脈穿刺中心靜脈置管的幾個(gè)操作細(xì)節(jié). 麻醉與監(jiān)護(hù)論壇, 2010,17(2):145-7

(9) Hong-Zhi Wang, Zhi-Yong Peng, Xiao-Yan Wen, Thomas Rimmelé, Jeffery V. Bishop, John A. Kellum*. N-acetylcysteine is effective for prevention but not for treatment of folic acid-induced acute kidney injury in mice. Crit Care Med. 2011,39(11):2487-2494

(10)Zhi-Yong Peng#, Hong-Zhi Wang#, Melinda J. Carter, Morgan V. Dileo, Jeffery V. Bishop, Fei-Hu Zhou, Xiao-Yan Wen, Thomas Rimmele′, Kai Singbartl, William J. Federspiel, Gilles Clermont, John A. Kellum*. Acute removal of common sepsis mediators does not explain the effects of extracorporeal blood purification in experimental sepsis. Kidney Int. 2012,81(4):363-369

2. 通訊作者論文

(1)董軍 李青 王宏志*.腫瘤患者術(shù)后嚴(yán)重肺栓塞(附 14 例分析).中國(guó)現(xiàn)代醫(yī)學(xué)雜志,2013,23(7):79-82

(2)陳仁雄 王宏志*.術(shù)中心跳驟停后超長(zhǎng)時(shí)間心肺復(fù)蘇術(shù)搶救成功1例. 中華麻醉學(xué)雜志. 2014,34(8):1023-4

(3)楊勇 王新朋 陳小杰 任宏 方華 王宏志*. B 型腦鈉肽對(duì)合并膿毒癥休克的腫瘤患者預(yù)后的價(jià)值. 廣東醫(yī)學(xué),2016,37(17):2631-3

(4)楊勇,陳小杰,陳仁雄,王新朋,方華,王宏志*. 結(jié)直腸癌患者術(shù)后肺部并發(fā)癥的危險(xiǎn)因素. 實(shí)用醫(yī)學(xué)雜志,2017,33(3):405-407

(5)Ren-Xiong Chen, Hong-Zhi Wang*, Jun Dong, Hong Ren, Xiao-Jie Chen, Jia-Xuan Xu, Yong Yang,and Guo-Dong Wang. Pulmonary embolism in non-brain tumor patients after surgery—a retrospective study in China. World J Surg Oncol. 2017, 15(1):22-7

(6)Jia-XuanXu, Jun Dong, Hong Ren, Xiao-Jie Chen, Yong Yang, Ren-Xiong Chen and GuoDong Wang, Hong-Zhi Wang. Incidence and risk assessment of venous thromboembolism in cancer patients admitted to intensive care unit for postoperative care. J BUON 2018; 23(1): 248-254

(7)徐稼軒,王宏志,董軍,陳小杰,楊勇,陳仁雄,王國(guó)棟. 食管癌術(shù)后急性肺損傷/急性呼吸窘迫綜合征的危險(xiǎn)因素分析.北京大學(xué)學(xué)報(bào)(醫(yī)學(xué)版),2018,50(6):1057-1062

(8)徐稼軒,王宏志*. 國(guó)內(nèi)腫瘤醫(yī)院重癥從業(yè)人員靜脈血栓栓塞癥預(yù)防管理知識(shí)和執(zhí)行力的多中心現(xiàn)狀調(diào)查. 中國(guó)中西醫(yī)結(jié)合急救雜志。2019,26(2):201-206

(9)王國(guó)棟,沈艷芬,董 靜,王新朋,王曉崢,鄭媛媛,郭雙雙,王宏志. 惡性腫瘤病人發(fā)生PICC相關(guān)性血栓的相關(guān)因素研究.腸外與腸內(nèi)營(yíng)養(yǎng). 2019, 26(6):331-336

(10)Yong Yang,Hong-Zhi Wang. Surgery in Cancer Patients: Risk Factors for Major Adverse Cardiac Events.Indian Journal of Surgery. Indian J Surg (2020) 82:1011-1015. DOI: 10.1007/s12262-020-02238-3

(11)Ren-Xiong Chen, Hong-Zhi Wang, Yong Yang, Xiao-Jie Chen. The risk factors on the prognosis of pulmonary embolism in tumor patients after the thoracic and abdominal surgery. Annals of Palliative Medicine. 2020;9(5):2982-2987.

(12)Ren-Xiong Chen, Zhou-Qiao Wu, Zi-Yu Li, Hong-Zhi Wang, Jia-Fu Ji. Health economic evaluation of patients with sepsis after gastrointestinal tumor surgery-a cost consequences analysis in China. J Gastrointest Oncol.2020;11(5):894-898.

(13)Guo-Dong Wang, Hong-Zhi Wang, Yan-Fen Shen, Jing Dong, Xin-Peng Wang, Xiao-Zheng Wang, Yuan-Yuan Zheng, Jie Chen, Shuang-Shuang Guo. The Influence of Venous Characteristics on Peripherally Inserted Central Catheter-Related Symptomatic Venous Thrombosis in Cancer.Cancer Management and Research. 2020;12:11909-11920.

(14)Guodong Wang, Hongzhi Wang, Yanfen Shen, Jing Dong,Xinpeng Wang, Xiaozheng Wang, Yuanyuan Zheng,Shuangshuang Guo. Association between ABO blood group and venous thrombosis related to the peripherally inserted central catheters in cancer patients. J Vasc Access. 2021;22(4):590-596. doi: 10.1177/1129729820954721. Epub 2020 Sep 3.

(15)Yong Yang, Jiahua Leng, Xiuyun Tian, Hongzhi Wang and Chunyi Hao. Brain natriuretic peptide and cardiac troponin I for prediction of the prognosis in cancer patients with sepsis. BMC Anesthesiol.2021; 21(1):159-66. doi:10.1186/s12871-021-01384-9.

(16)Ren-Xiong Chen, Zhou-Qiao Wu, Zi-Yu Li, Hong-Zhi Wang, Jia-Fu Ji. Prognostic predictors in patients with sepsis after gastrointestinal tumor surgery: A retrospective study. World J Gastrointest Surg. 2021;13(3):256-266. doi: 10.4240/wjgs.v13.i3.256.

(17)Yong Yang, Jiahua Leng, Renxiong Chen, Hongzhi Wang1, Chunyi Hao. Correlation between early brain natriuretic peptide level and mortality in cancer patients with septic shock. Ann Palliat Med. 2021; 10(4):4214-4219. doi:10.21037/apm-20-2212.Epub 2021 Mar 23.

(18)Xiang Li#, Guodong Wang#, Kun Yan, Shanshan Yin,Hongzhi Wang,Yanjie Wang,Xiumei Bai,and Yanfen Shen. The Incidence, Risk Factors, and Patterns of Peripherally Inserted Central Catheter-Related Venous Thrombosis in Cancer Patients Followed Up by Ultrasound. Cancer Manag Res. 2021;13:4329-4340. doi: 10.2147/CMAR.S301458. eCollection 2021.

(19)Xinpeng Wang#, Yong Yang#, Jing Dong, Xiaozheng Wang, Yuanyuan Zheng, Jie Chen, Yanfen Shen,Hongzhi Wang. A comparative study on the tip position of peripherally inserted central catheter inserted at two forward P-wave amplitudes by intracavitary electrocardiogram in cancer patients. Ann Palliat Med. 2021;10(10):10228-10235. doi: 10.21037/apm-21-1893. Epub 2021 Aug 24.

(20)Xinpeng Wang*, Yong Yang* , Jing Dong, Xiaozheng Wang,Yuanyuan Zheng, Jie Chen, Yanfen Shen,Hongzhi Wang. Analysis of six cancer patients with persistent left superior vena cava identified during central venous access device placement via an intracavitary electrocardiogram. J Vasc Access. 2021 Sep 29;11297298211045576. doi: 10.1177/11297298211045576.

(21)Ren-Xiong Chen, Hong-Zhi Wang, Yong Yang, Xiao-Jie Chen. Risk factors for failure of subclavian vein catheterization: a retrospective observational study. Braz J Anesthesiol.2022; 72(2):228-31. doi.org/10.1016/j.bjane.2021.02.032

(22)陳仁雄,王宏志,沈艷芬,董 靜. 減少鎖骨下靜脈穿刺并發(fā)癥方法探討(附1 480例分析). 腸外與腸內(nèi)營(yíng)養(yǎng).2021;28(2):72-4,78

(23)陳仁雄,王宏志.乳腺癌術(shù)后肺栓塞 27 例臨床特征分析. 中國(guó)腫瘤外科雜志. 2021;13(3):258-60

(24)Yong Yang, Jun Dong, Yang Li, Renxiong Chen, Xiuyun Tian, Hongzhi Wang, Chunyi Hao. Development and validation of a nomogram for predicting the prognosis in cancer patients with sepsis. Cancer Med. 2022;11(12):2345-2355. doi: 10.1002/cam4.4618. Epub 2022 Feb 18.

參編書目:

1. 顧晉主編,《直腸肛門部惡性腫瘤》,北京大學(xué)醫(yī)學(xué)出版社,2007年2月,本人編寫第二十九章第七節(jié):多原發(fā)結(jié)直腸癌。

2. 陳克能 許紹發(fā)主譯,《普通胸外科圍術(shù)期治療手冊(cè)》,人民衛(wèi)生出版社,2007年9月,本人負(fù)責(zé)翻譯第六章第三節(jié):胸外科患者的圍術(shù)期液體管理。

3. 朱曦等主編、36人參編,《重癥搶救﹒ICU醫(yī)生工作手記》,北京大學(xué)醫(yī)學(xué)出版社,2016年5月,本人編寫第二章首篇《值得信賴的幕后英雄-ICU醫(yī)生》。

4. 周飛虎、康紅軍主譯,《重癥醫(yī)學(xué)·循證實(shí)踐》,山東科學(xué)技術(shù)出版社,2017年6月,本人翻譯第42章:我們?cè)鯓硬拍鼙O(jiān)控膿毒癥時(shí)的微循環(huán),是否能改善預(yù)后,第87章:哪些因素影響家庭做出撤銷生命支持的決定。

5. 樊代明總主編,《整合腫瘤學(xué)》,世界圖書出版西安有限公司,2021年6月,本人編寫《基礎(chǔ)卷·治療分冊(cè)·第十五章第七節(jié)(腫瘤患者的血栓栓塞癥與肺動(dòng)脈栓塞)》。