張曉燕，醫(yī)學(xué)博士，知名專家、副教授、碩士生導(dǎo)師。2009年獲北京大學(xué)影像醫(yī)學(xué)與核醫(yī)學(xué)博士學(xué)位，同年于北京大學(xué)腫瘤醫(yī)院醫(yī)學(xué)影像科工作至今，現(xiàn)任醫(yī)學(xué)影像科黨支部書(shū)記。

學(xué)術(shù)兼職：中華醫(yī)學(xué)會(huì)放射學(xué)分會(huì)MRI學(xué)組委員、中華醫(yī)學(xué)會(huì)放射學(xué)分會(huì)大數(shù)據(jù)AI工作委員會(huì)委員、中國(guó)醫(yī)學(xué)裝備協(xié)會(huì)磁共振專委會(huì)腹部學(xué)組委員、北京醫(yī)學(xué)會(huì)放射學(xué)分會(huì)青年委員會(huì)副主任委員。

多年來(lái)從事體部腫瘤的影像診斷，尤其在結(jié)直腸腫瘤影像診斷及治療療效評(píng)價(jià)方面積累較多經(jīng)驗(yàn)，并開(kāi)展了系統(tǒng)深入的臨床研究，主要研究成果相繼發(fā)表于影像學(xué)頂刊《Radiology》、外科學(xué)權(quán)威期刊《Annals of Surgery》、國(guó)際腫瘤學(xué)權(quán)威期刊《Clnincal Cancer Research》、《Radiotherapy & Oncology》、《Ann Surg Oncol》等，代表性論文共被引用 300 次，他引275次，為Web of Science高被引論文。連續(xù)兩次獲得“中國(guó)十佳消化道領(lǐng)域臨床研究”獎(jiǎng)項(xiàng)。參與編寫論著和譯著4部。作為第二完成人獲得中國(guó)抗癌協(xié)會(huì)科技獎(jiǎng)二等獎(jiǎng)1項(xiàng)。擔(dān)任國(guó)家衛(wèi)健委 《中國(guó)結(jié)直腸癌診療規(guī)范(2017版、2020版)》的影像學(xué)執(zhí)筆人。

主持課題：國(guó)家自然科學(xué)基金青年科學(xué)基金項(xiàng)目(結(jié)題)、國(guó)家自然科學(xué)基金面上科學(xué)項(xiàng)目(在研)、科技部國(guó)家重點(diǎn)研發(fā)計(jì)劃“診療裝備與生物醫(yī)用材料”重點(diǎn)專項(xiàng)(在研)等。

近年主要的科研方向包括：1. 多模態(tài)影像技術(shù)對(duì)直腸癌分期、療效評(píng)價(jià)和預(yù)后預(yù)測(cè);2.人工智能技術(shù)在直腸癌新輔助治療療效評(píng)價(jià)和預(yù)后風(fēng)險(xiǎn)模型建立中的應(yīng)用探索。

發(fā)表論文

近5年發(fā)表文章：

(1) Xiao-Yan Zhang; Lin Wang; Hai-Tao Zhu; et al; Predicting Rectal Cancer Response to Neoadjuvant Chemoradiotherapy Using Deep Learning of Diffusion Kurtosis MRI.Radiology, 2020, 296(1): 56-64.

(2) Xiao-Yan Zhang; Shuai Wang; Xiao-Ting Li; et al; MRI of Extramural Venous Invasion in Locally Advanced Rectal Cancer: Relationship to Tumor Recurrence and Overall Survival.Radiology, 2018, 289(3): 677-685.

(3) Xiao-Yan Zhang; Xiao-Ting Li; Yan-Jie Shi;et al; Correlation between the Distance to Mesorectal Fascia and Prognosis of cT3 Rectal Cancer: A Multicenter Study Results of China. Dis Colon Rectum, 2022;65(3):322-332.

(4) Lin Wang; Xiao-Yan Zhang; Yi-Ming Zhao; et al; Intentional Watch & Wait or Organ Preservation Surgery Following Neoadjuvant Chemoradiotherapy Plus Consolidation CAPEOX for MRI-defined Low-risk Rectal Cancer: Findings from a Prospective Phase 2 Trial (PKUCH-R01 Trial, NCT02860234). Annals of Surgery, 2023, 277(4): 647-654.

(5) Hai-Tao Zhu;Xiao-Yan Zhang; Yan-Jie Shi; et al; The Conversion of MRI Data With Multiple b-Values into Signature-Like Pictures to Predict Treatment Response for Rectal Cancer. J. MAGN. RESON. IMAGING, 2022, 56(2): 562-569.

(6) Zhenyu Liu; Xiao-Yan Zhang; Yan-Jie Shi; Lin Wang; Hai-Tao Zhu; Zhenchao Tang; Shuo Wang; Xiao-Ting Li; Jie Tian; Ying-Shi Sun ; Radiomics analysis for evaluation of pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. Clinical Cancer Research, 2017, 23(23): 7253-7262.

(7) Zhang XY; Liu XZ; Li XT; et al; MRI measurements predict major low anterior resection syndrome in rectal cancer patients. Int J Colorectal Dis, 2022, 37(6): 1239-1249.

(8) Tang, Zhenchao; Zhang,Xiao Yan; Liu, Zhenyu; Li, Xiao Ting; Shi, Yan Jie; Wang, Shou; Fang, Mengjie; Shen, Chen; Dong, Enqing; Sun, Ying Shi; Tian, Jie ; Quantitative analysis of diffusion weighted imaging to predict pathological good response to neoadjuvant chemoradiation for locally advanced rectal cancer. Radiotherapy and Oncology, 2019, 132: 100-108.

(9) 中華醫(yī)學(xué)會(huì)外科學(xué)分會(huì)結(jié)直腸外科學(xué)組; 北京市醫(yī)學(xué)影像質(zhì)量控制和改進(jìn)中心 ; 結(jié)直腸癌病人影像學(xué)檢查臨床適用性評(píng)價(jià)指南(2021版). 中國(guó)實(shí)用外科雜志, 2021, 41(10): 1104-1110.

(10) 中國(guó)醫(yī)師協(xié)會(huì)結(jié)直腸腫瘤專業(yè)委員會(huì)診療技術(shù)專委會(huì); 中華醫(yī)學(xué)會(huì)放射學(xué)分會(huì)腹部學(xué)組 ; 直腸癌MR掃描及結(jié)構(gòu)式報(bào)告規(guī)范專家共識(shí). 中華放射學(xué)雜志, 2021, 55(11): 1121-1127.

(11) 張曉燕; 朱海濤; 王林; 李曉婷; 史燕杰; 朱匯慈; 孫應(yīng)實(shí) ; 基于MRI影像組學(xué)模型預(yù)測(cè)局部進(jìn)展期直腸癌新輔助放化療后淋巴結(jié)狀態(tài)的研究. 中華放射學(xué)雜志, 2017, 51(12): 926-932.